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After inhalation of 10 to 20% of the dose enters the testosterone propionate buy. The rest of the unit is delayed or is deposited in the oropharynx and then swallowed. Portion of the dose that has remained in the respiratory tract, is absorbed by lung tissues without being metabolized in the lungs, and into the bloodstream. When injected into the blood system, it may metabolizmrovatsya in the liver and excreted predominantly in the urine in unchanged form or in the form of phenolic sulphate. Part of the dose received by the gastro-intestinal tract, absorbed and undergoes extensively metabolized during the first pass through the liver, turning into phenol sulfate . Unchanged drug and conjugate are derived mainly from the urine. Most of the dose of salbutamol administered intravenously, orally or by inhalation, is displayed for 72 hours. The degree of salbutamol binding to plasma proteins is 10%. Maximum plasma concentration – 30 ng / ml. The half – 3,7-5 hours.

 

Indications
Prevention and relief of testosterone propionate buy bronchospasm in bronchial asthma, chronic obstructive pulmonary disease, chronic bronchitis, emphysema.

Contraindications
: Hypersensitivity to any component of the drug, arrhythmias (paroxysmal tachycardia, polygons ventricular arrythmia), myocarditis, heart defects, aortic stenosis, coronary heart disease, tachyarrhythmias, hyperthyroidism, decompensated diabetes, glaucoma, seizures, which pyloroduodenal narrowing, renal or hepatic impairment , pregnancy, concomitant use of nonselective beta-blockers, children up to 2 children.
With care – chronic heart failure, hyperthyroidism, hypertension, pheochromocytoma.

Application of pregnancy and lactation
is contraindicated during pregnancy.
During the period of lactation is appointed only in cases where the expected benefit to the mother outweighs any possible risk to the child.

Dosage and administration Adults testosterone propionate buy and children over 12 years: 100-200 MW Salamol Eco (1-2 inhalation doses) for the relief of asthma attacks. To control the flow of mild asthma – 1-2 dose 1-4 times a day and an average disease severity – at the same dosage in combination with other drugs protivoastmatncheskimi. To prevent asthma physical effort – for 20-30 minutes before loading dose of 1-2 at the reception. Children from 2 to 12 years: the development of bronchial asthma attack, and to prevent attacks of asthma associated with exposure to the allergen or exercise-induced, the recommended dose is 100-200 mg (1 or 2 inhalations). The daily dose should not exceed salbutamol 800 mcg (8 inhalations).

 

Side effects
Salamol Eco can cause tremors of fingers, which is a typical side effect of all agonists .beta.-2 adrenergic receptors. There may be headache, dizziness, irritability, anxiety, sleep disorder, insomnia, increased peripheral vascular (flushing of skin), small compensatory increase in heart rate, increased blood pressure, the appearance of pain in the chest, arfalgiya. May develop hypersensitivity reactions (including angioedema, urticaria, erythema, nasal congestion, bronchospasm, arterial giiotenziyu and collapse); muscle cramps, nausea, vomiting, dyspepsia.
Inhaled medicines may cause paradoxical bronchospasm.
Inhaled medicines may cause irritation of the mucous membranes of the mouth and pharynx (throat), coughing.
salbutamol therapy can cause hypokalemia, which may pose a serious danger to the patient, as well as reversible metabolic abnormalities such as increased blood glucose concentration.
The drug can cause excitation testosterone propionate buy and increase physical activity in children.
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